Abstract By arranging slope seismic monitoring instruments in Wutong village, Gongxian county, Yibin, we collect data from the Xingwen county MS3.1, Gongxian MS4.5 and Changning county MS4.6 earthquakes. We filter and correct the seismic response data of Gongxian aftershocks collected at 1#, 2# monitoring points on the monitoring profile, and the magnitude, elevation after the seismic response caused by azimuth and other factors to the slope. We infer that: 1) the distance between the half wavelength of the local seismic wave and some specific parts of the mountain is close, the slope terrain and the wave crest of the seismic wave are coupled, and the topographic amplification effect is significant, up to 2.765 times of the reference point. Here, the mountain is more likely to produce large-scale shaking, which is more likely to cause mountain geological disasters. 2) Through the analysis of the Gongxian MS4.5 and Changning county MS4.6 earthquakes, we infer that when the seismic wave propagates along special parts(such as ridge, etc), the seismic acceleration and arias intensity are more significant. 3) Through the analysis of the change of seismic acceleration of seismic data, we conclude that under the action of seismic load, the acceleration response of slope increases with increased magnitude. 4) With the change of elevation and magnitude, the seismic acceleration and arias intensity of monitoring points also change, and we conclude that elevation and magnitude have amplification effect on the seismic response of slope. 5) Under the coupling effect of elevation and micro landform, the seismic acceleration also has obvious amplification effect.