Abstract：In this paper, the interaction of faults is studied based on the calculation of Coulomb failure stress. From the two aspects of source fault and receiver fault, five kinds of seismic fault models are selected to study the distribution characteristics of Coulomb failure stress when these five fault models are used as source faults and receiver faults, and we analyze the influence of the different slip mechanisms of the source fault and the receiver fault on the distribution of the Coulomb failure stress. On the basis of the analysis, it is found that the fault and slip mechanism of the fault are closely related. The strike-slip fault also has a certain relationship with the left and right rotation. In addition to the skew fault, the interaction between the other faults shows a certain symmetrical relationship.