Abstract:On the basis of the Total Electron Content (TEC) obtained from International GNSS Service (IGS) and the VTEC derived from the GPS observation data from the reference stations of Crustal Movement Observational Network of China and using the method of moving average,we have processed and analyzed the ionospheric TEC prior to the Myanmar Ms7.2 earthquake. The results show that the anomalous reduction of TEC occurred on 6-8 day prior to the earthquake and the anomalous increase of TEC occurred on the 3rd day prior to the earthquake may be related to the geomanetic disturbance on Mar. 21. Due to the time is close to the occuring moment of the event, it can be concluded that the observed anomalous reduction of ionospheric TEC on Mar. 16, 17 and 18 and the conjugated structure of the anomalous reduction on Mar. 18 is possibly related to the earthquake excluding the effect of solar activity and geomagnetic disturbance.